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Average fit based on the ratings of 1 customer:
"Target dynamic wrinkles with our potent 10% Acetyl Hexapeptide-8 serum (Argireline ). This high-strength peptide formula helps relax facial muscle contractions to visibly reduce the appearance of forehead lines, crow's feet and expression wrinkles - delivering smoother, more youthful-looking skin without needles. Lightweight, fast-absorbing and non-irritating, it's perfect for daily anti-ageing routines.
Key Benefits of This 10% Acetyl Hexapeptide-8 Serum
Targets Dynamic Wrinkles - Helps relax muscle contractions to soften expression lines
Smooths Forehead, Eyes & Mouth Area - Visibly reduces crow's feet, frown lines and smile wrinkles
Non-Invasive Anti-Ageing - Botox-like smoothing without injections, pain or downtime
Lightweight & Layerable - Absorbs quickly; works under makeup or with moisturisers/SPF
Gentle for Most Skin Types - Low irritation potential; suitable for sensitive skin when patch-tested.
The fast-absorbing, water-based texture makes it easy to apply precisely to problem zones or all over the face for preventative care.
Our 10% Acetyl Hexapeptide-8 serum (commonly known as Argireline ) offers a powerful, non-invasive topical solution. This high-concentration peptide works by helping to relax the facial muscles responsible for dynamic wrinkles, delivering visible smoothing and a more rested, youthful appearance without the need for needles or downtime.
Why 10% Acetyl Hexapeptide-8 Is a Standout Choice
Acetyl Hexapeptide-8 is a synthetic peptide that mimics the N-terminal end of SNAP-25, interfering with the neurotransmitter release that triggers muscle contractions. At 10% - a clinically inspired, high-strength concentration popular in leading formulations - it provides meaningful relaxation of expression lines. Key visible benefits include:
Reduction in wrinkle depth, particularly on the forehead, around the eyes (crow's feet) and near the mouth
Smoother skin texture and a more relaxed, rested look
Support for overall skin smoothness and youthful bounce
Gentle, non-irritating action suitable for daily use
Studies and manufacturer testing (including in-vivo trials) have shown that 10% Acetyl Hexapeptide-8 applied consistently can decrease wrinkle depth by up to 17% in 15 days around the eyes, with continued improvements over 4-8 weeks. It is especially effective for dynamic (movement-induced) lines rather than deep structural ageing, making it an excellent ""quick-fix"" complement to collagen-boosting actives like vitamin C, retinol or other peptides.
How to use:
After cleansing and applying a treatment tonic, apply 2-3 drops to targeted areas: forehead, between brows, around eyes and smile lines. Gently pat in until absorbed. Use AM and/or PM. For enhanced results, follow with a moisturiser and broad-spectrum SPF 30+ in the daytime. Start daily; it is gentle enough for most users from the first application. Visible softening of lines often begins in 2-4 weeks, with optimal smoothing after 8-12 weeks of consistent use.
Who Should Choose This Serum?
Those with dynamic expression lines (forehead, crow's feet, frown lines)
People seeking a non-invasive, topical alternative to Botox or fillers
Early or preventative anti-ageing routines (20s-40s+)
Sensitive skin wanting peptide power without irritation
Anyone layering peptides for comprehensive wrinkle care
Patch test first. Consult a dermatologist if pregnant, breastfeeding or using prescription treatments.
Fundamentals Skincare is
Vegan friendly
Cruelty-free
Cosmeceutical grade
Fragrance-free
Made in South Africa
Dermatologically Tested and Approved
What's in the box
1 x Fundamentals Skincare Amber Glass Bottle"
Brand
Fundamentals Skincare
Volume
30ml
Simply choose the option that best suits you at checkout, and we’ll ship it immediately once the order is approved.
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From R46.25 every 2 weeks
Pay for your order in either 4 interest-free payments over 6 weeks OR 3 interest-free payments over 3 paydays – all at 0% interest.
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R61.66 every month
Super simple and easy sign-up. Pay for your purchases over 3 instalments, interest and fee free.
4.67
(3 ratings)
Affordable and effective
Forever a fave❤️ third time purchasing this. My face loves it
R185